Description
Levemir FlexPen 100U/ml (Insulin detemir)
What is Levemir FlexPen 100U/ml (Insulin detemir) ?
Levemir FlexPen 100U/ml (Insulin detemir) is a long-acting insulin that lowers blood sugar by encouraging tissues to take excess glucose, discouraging the body from making more glucose, preventing the breakdown of fat and protein, and helping the body regulate levels of blood sugar.
Levemir FlexPen 100U/ml (Insulin detemir) is the brand name for the prescription drug insulin detemir. It’s used to treat type 1 and type 2 diabetes.
Levemir FlexPen 100U/ml (Insulin detemir) is an insulin pen syringe prefilled with Levemir. It’s designed to make the drug easier to use.
Forms
Each mL of sterile, aqueous, clear, colourless and neutral solution, contains salt-free anhydrous insulin detemir 100 units (14.2 mg/mL). One unit of Levemir corresponds to one IU of human insulin. Nonmedicinal ingredients: disodium phosphate dihydrate, glycerol, mannitol, metacresol, phenol, sodium chloride, acetate, and water for injection. Hydrochloric acid and/or sodium hydroxide may be added to adjust pH (approximately 7.4).
How to use ?
The recommended dose of insulin depends on how much natural insulin your pancreas is producing and how well your body is able to use the insulin. Your doctor or diabetes educator will determine the appropriate dose for you according to various lifestyle factors and the blood glucose values obtained while monitoring your blood glucose.
Your dose of insulin should be injected subcutaneously (under the skin) exactly as instructed by your doctor or diabetes educator. Do not inject insulin detemir into the vein and do not use insulin detemir in insulin infusion pumps. Each 1 mL of insulin contains 100 units. Insulin detemir is injected under the skin once or twice daily. In addition to insulin detemir, a fast-acting insulin is usually used to control the impact of food intake on blood glucose levels during the day. There are many variations of insulin dosing.
Insulin detemir should be clear and colourless. Do not use the insulin if you notice anything unusual in the appearance of the solution, such as cloudiness, discoloration, or clumping. It is not necessary to shake or rotate the vial before use. It should not be mixed with any other insulins.
You can store unopened vials of Levemir at room temperature or in the refrigerator, but toss any vial that’s been open for more than 42 days, even if isn’t empty.
Never freeze Levemir or use any Levemir that’s been frozen. Keep Levemir away from heat and light.
Side effects
Common Side Effects of Levemir:
Low blood sugar
Joint pain
Itching
Rash
Lumps of fatty tissue under the skin where you inject the medication
Getting the flu
Infection of the nose, throat, or airways or all three areas
Swelling in the feet, ankles, orlower legs or all three areas
Weight gain
Headache
Serious Side Effects of Levemir:
Low blood sugar
Low potassium level
Allergic reactions, including life-threatening anaphylaxis, in which your throat and tongue may swell, you break out in hives, or you have trouble breathing or you have all three symptoms
Interactions
This includes prescriptions and over-the-counter medications, vitamins and other dietary supplements (nutritional shakes, protein powders, etc.), herbal remedies, and illegal and recreational drugs.
Do not use Levemir if you are taking the following drugs:
Beta blockers, such as carvedilol (Coreg, Coreg CR), atenolol (Tenormin), or propranolol (Inderal, Inderal LA)
Rosiglitazone (Avandia)
Pramlintide (Symlin).
The following drugs can interact with Levemir and cause serious symptoms:
Blood pressure medications, such as many ACE inhibitors: captopril (Capoten), Ramipril (Altace), quinapril l (Accupril), and trandolapril (Mavik)
Diuretics, such as bumetanide (Bumex), hydrochlorothiazide (Esidrix, Microzide) and chlorthalidone (Thalitone)
Birth control pills and hormone replacement therapy (HRT) medications that contain estrogen or estradiol
Diabetes medications, such as glyburide (Diabeta, Glynase), glipizide (Glucotrol), acarbose (Precose), nateglinide (Starlix), miglitol (Glyset)
Corticosteroids, such as prednisone (Rayos, Deltasone), methylprednisolone (Medrol, Depo-Medrol, Solu-Medrol, A-Methapred), and budesonide (Entercort EC, Uceris, Pulmicort, Rhinocort)
Also, many different herbs and supplements like aloe vera, bitter melon, ginger, fenugreek, and chromium may lower your blood sugar.
Glucosamine, a popular ingredient in many supplements for osteoarthritis and knee pain, may increase your blood sugar level.
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